While one player takes on the role of Thanos on a crusade to change the universe as we know it, 1-5 other players must deploy iconic heroes to defeat him before he can achieve his aims.
Throughout the game, players take turns drawing a card and playing a card, then executing its effect. Hero players can call upon the likes of Iron Man, Spider-man, Thor, and Scarlet Witch for their abilities to battle and gather intel about their opponent’s schemes. A worthy adversary, Thanos plays with a two-card hand, drawing from his own deck of minions and powerful Infinity Stones. The heroes will have to use their abilities in strategic combinations to knock his health down to zero before he can do the same to them—or find all six Infinity Stones and win with a snap of his fingers. Who will prevail in this battle for the universe?